Azadirachtin is the most important compound found in neem oil, it’s the one responsible for getting rid of insects and different kinds of bacteria, in other words, it’s the one responsible for getting rid of those nasty bugs in your garden! However, is it toxic?
The answer is no, azadirachtin’s toxicity is completely negligible, and although it affects about 200 types of insects by acting as an antifeedant and growth disruptor, it’s completely safe for us humans.
Studies have been done on different mammals and they have shown that azadirachtin’s toxicity is: > 3,540 mg/kg, this makes it practically non-toxic for us humans.
What about azadirachtin’s toxicity for the good insects in your garden?
Rest assured, azadirachtin is completely safe for those beneficial insects you have in your garden, such as ladybugs, it’s because azadirachtin only acts as an antifeedant on insects that feed on plants, not on insects that feed on other insects, you need to understand that those bad insects for your garden, like the Japanese beetles, are going to munch directly on your plants, and if you have already sprayed them with neem oil or applied neem concentrate, then they are going to directly ingest azadirachtin which is going to interfere with their system.
What about azadirachtin toxicity for the soil?
Azadirachtin is completely biodegradable, and the wonderful thing is that it degrades in about 100 hours after being exposed to sunlight and water.